History of Multiple Sclerosis

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The first pathologists to investigate some of MS signs and symptoms were the Frenchman Jean Cruveilhier and the Englishman Robert Carwell . They however did not identify it as a distinct condition. The disease was officially discovered by the French Neurologist Jean-Martin Charcot (1825 – 1893) in 1868 who – on the basis of his personal clinical observations – called the condition Sclerose en Plaque. He was the first to describe scientifically, document and name the disease process.

The first three MS signs recognised by Charcot, which are now known as Charcot’s triad, are:

NystagmusRegression to telegraphic speech, which is the speech during the stage of language acquisition in children.Intention Tremor, which is a disorder consisting of wide tremor that occur when a person performs a voluntary movement.

Charcot also observed cognition changes, affecting the memory and cognitive capacity.